博士后 研究方向:Functional characterization and mechanism of gene for ER stress tolerance in Arabidopsis thaliana 电子邮箱:hakim_gaadwani@outlook.com, hakim@scau.edu.cn
个人简介
Volunteer in Cotton conference at Huazhong Agricultural University, Wuhan, Hubei, China.
承担主要科研项目:
1.Functional characterization and mechanism of gene for ER stress tolerance in Arabidopsis thaliana
2.CRISPR-Cas9 system for cotton genome editing
3.Off-target effects of CRISPR-Cas 9 system
4.High Efficient and Precise Base Editing of C•G to T•A in the Cotton
代表性论文:
1, Hakim Manghwar, Bo Li, Xiao Ding, Amjad Hussain, Keith Lindsey, Xianlong Zhang§, Shuangxia Jin§ (2020). CRISPR/Cas Systems in Genome Editing: Methodologies and Tools for sgRNA Design, Off-target Evaluation and Strategies to Mitigate Off-target Effects. Advanced Science, 2020, 1902312, DOI: 10.1002/advs.201902312.
2, Hakim Manghwar, Keith Lindsey, Xianlong Zhang§, Shuangxia Jin§. CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing (2019). Trends in Plant Science. Volume 24, Issue 12, December 2019, Pages 1102-1125. https://doi.org/10.1016/j.tplants.2019.09.006.
3, Li, Jianying†; Manghwar, Hakim† (First co-author); Sun, Lin†; Wang, Pengcheng; Wang, Guanying; Sheng, Hanyan; Zhang, Jie; Liu, Hao; Qin, Lei; Rui, Hangping; Li, Bo; Lindsey, Keith; Daniell, Henry; Jin, Shuangxia*; Zhang, Xianlong (2018). Whole genome sequencing reveals rare off‐target mutations and considerable inherent genetic or/and somaclonal variations in CRISPR/Cas9‐edited cotton plants. Plant Biotechnology Journal (2018), pp. 1–11, https://doi.org/10.1111/pbi.13020.
4, Hakim Manghwar, Amjad Hussain, Abid Ullah, Summia Gul, Muhammad Shaban, Aamir Hamid Khan, Musrat Ali, Syed Gul Abbas Shah Sani, Hassan Javed Chaudhary, Muhammad Farooq Hussain Munis* (2018). Expression analysis of defense related genes in wheat and maize against Bipolaris sorokiniana. Physiological and Molecular Plant Pathology 103: 36–46.
5, Hakim, Abid Ullah, Amjad Hussain, Muhammad Shaban, Aamir Hamid Khan, Muna Alariqi, Summia Gul, Zhang Jun, Sun Lin, Jianying Li, Shuangxia Jin*, Muhammad Farooq Hussain Munis* (2018). Osmotin: A plant defense tool against biotic and abiotic stresses. Plant Physiology and Biochemistry 123: 149–159.
6, Hakim, S. Naz, S. Gul, H.J. Chaudhary and M.F.H. Munis* (2015). FIRST REPORT OF RHIZOPUS ORYZAE CAUSING FRUIT ROT OF CITRUS MEDICA L. IN PAKISTAN. Journal of Plant Pathology, 97(1), 209–220.
7, Hakim, S. Naz, F. Liaquat, S. Gul, H.J. Chaudhary and M.F.H. Munis* (2015). PRESENCE OF BACILLUS PUMILUS CAUSING FRUIT ROT OF FICUS LACOR IN PAKISTAN. Journal of Plant Pathology, 97(3), 541–551.
奖励荣誉:
•Certificate of secured second position in poster presentation in 2nd SINO-PAK International Conference on Innovations in Cotton Breeding & Biotechnology, November 26–27, 2018 at Muhammad Nawaz Shareef University of Agriculture Multan, Pakistan.
•Certificate of participation in international conference on “Application of Molecular Biology in Medicine and Agriculture”.
•Certificate of model representation on “International Biodiversity Day”.
•Awarded “Chinese Government Scholarship” from 2015-2019